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American Society of Microbiology ABMM Sample Questions (Q151-Q156):
NEW QUESTION # 151
A clinical microbiology laboratory is implementing a new MALDI-TOF mass spectrometry system for bacterial identification. For accurate identification, the system relies on comparing the protein profile of an unknown isolate to:
- A. A database of bacterial cell wall lipid compositions.
- B. A database of known bacterial ribosomal RNA sequences.
- C. A database of protein mass spectra from well-characterized organisms.
- D. A database of antibiotic resistance genes.
Answer: C
NEW QUESTION # 152
A microbiology laboratory receives a wound swab from a patient with a chronic, non-healing ulcer. Culture yields a Gram-positive, branching filamentous bacterium that is partially acid-fast. The MOST likely genus is:
- A. Mycobacterium
- B. Nocardia
- C. Actinomyces
- D. Streptomyces
Answer: B
NEW QUESTION # 153
A Klebsiella pneumoniae isolate from a bloodstream infection shows the following susceptibility profile:
Meropenem (MIC = 8 µg/mL, R), Imipenem (MIC = 16 µg/mL, R), Ertapenem (MIC = 4 µg/mL, R), Ceftazidime/avibactam (MIC = 1 µg/mL, S), Aztreonam (MIC = 32 µg/mL, R). Which resistance mechanism is most strongly suggested by this pattern?
- A. AmpC beta-lactamase hyperproduction coupled with porin loss
- B. Metallo-beta-lactamase (MBL) production
- C. Klebsiella pneumoniae Carbapenemase (KPC) production
- D. Extended-Spectrum Beta-Lactamase (ESBL) production alone
Answer: C
NEW QUESTION # 154
Acyclovir is a commonly used antiviral agent effective against Herpes Simplex Virus (HSV) and Varicella- Zoster Virus (VZV). Its selective toxicity relies on which initial step for activation within infected cells?
- A. Monophosphorylation primarily by viral thymidine kinase
- B. Phosphorylation by host cell mitochondrial kinases
- C. Blocking viral entry through competitive inhibition of cellular receptors
- D. Direct inhibition of viral RNA polymerase activity
Answer: A
NEW QUESTION # 155
A patient with cystic fibrosis experiences a pulmonary exacerbation. Sputum culture grows a mucoid strain of Pseudomonas aeruginosa. The mucoid phenotype is primarily due to the overproduction of:
- A. Pyocyanin
- B. Alginate
- C. Exotoxin A
- D. Elastase
Answer: B
NEW QUESTION # 156
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